In a mixing bowl, combine mayonnaise, sour cream, buttermilk, lemon juice, Worcestershire sauce, garlic powder, onion powder, salt, and black pepper.
Whisk or blend the ingredients until well combined and smooth. If desired, you can use a blender or food processor for a smoother texture.
Add the crumbled blue cheese to the mixture and gently fold it in, leaving some chunks for texture.
Taste the flavor of the dressing and adjust the seasonings according to your choice. You can add more lemon juice, salt, or black pepper if desired.
Transfer the dressing to an airtight container and refrigerate for at least one hour to allow the flavors to meld together.
Serve chilled and drizzle over salads, vegetables, or use as a dipping sauce for wings.