In a skillet, sauté the sliced yellow squash and chopped onions in butter until tender.
Drain any excess liquid.
Mix the Ingredients
In a large mixing bowl, combine the sautéed squash and onions with shredded cheddar cheese, beaten eggs, milk, salt, pepper, garlic powder, and onion powder.
Mix well until all ingredients are evenly combined.
Layer and Top
Transfer the mixture to a greased baking dish, spreading it evenly.
Sprinkle crushed buttery crackers on the mixture to add a delightful and crunchy texture.
Bake
Place the baking dish in the preheated oven and bake for approximately 25-30 minutes or until the casserole is set and the top is golden brown.